Urea is an organic compound that is sometimes used in the production of vaccines. Its primary purpose in vaccine manufacturing is as a stabilizer and preservative, and it serves several functions:

  1. Stabilization: Urea can help stabilize the vaccine by preserving the integrity and activity of the vaccine's antigens (the components that stimulate the immune response). This is particularly important for ensuring that the vaccine remains effective over time, even during storage and transportation.
  2. Preservation: Urea can act as a preservative by inhibiting the growth of microorganisms, such as bacteria and fungi, in the vaccine formulation. This helps prevent contamination and maintains the vaccine's quality and safety.
  3. Tonicity Adjustment: Urea may be used to adjust the tonicity (osmolarity) of the vaccine solution. Tonicity adjustment ensures that the vaccine solution has an appropriate balance of solutes, which can impact its stability and compatibility with the body's tissues.